mAdb Users Note: The mAdb BRBArraytools Format Retrieval Tool provides an easy way to import your data into BRBArrayTools. BRB ArrayTools Developed by: Dr. Richard Simon & Amy Peng Lam BRB ArrayTools is an integrated package for the visualization and statistical analysis of DNA microarray gene expression data developed by the Biometric Research Branch of the National Cancer Institute. It was developed by professional statisticians experienced in the analysis of microarray data and involved in the development of improved methods for the design and analysis of microarray based experiments. The array tools package utilizes an Excel front end as this makes the system portable and not tied to any database. The input data is assumed to be in the form of Excel spreadsheets describing the expression values and a spreadsheet providing user-specified phenotypes for the samples arrayed. The analytic and visualization tools are integrated into Excel as an add-in. The analytic and visualization tools themselves are developed in the powerful R statistical system, in C and Fortran programs and in Java applications. Visual Basic for Applications is the glue that integrates the components and hides the complexity of the analytic methods from the user. The system incorporates a variety of powerful analytic and visualization tools developed specifically for microarray data analysis. BRB ArrayTools is available to government users free of charge at http://linus.nci.nih.gov/BRB-ArrayTools.html The web site also contains a message board for users to communicate with the developers and each other. For questions about BRB ArrayTools, contact Dr. Richard Simon (rsimon@nih.gov).

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